Mostrati risultati da 1 a 20 di 150
Titolo Data di pubblicazione Autore(i) Rivista Editore
Inhibition of the drug efflux activity of Ptch1 as a promising strategy to overcome chemotherapy resistance in cancer cells 1-gen-2022 Kovachka, S.; Malloci, G.; Simsir, M.; Ruggerone, P.; Azoulay, S.; Mus-Veteau, I. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY -
Molecular rationale for the impairment of the MexAB-OprM efflux pump by a single mutation in MexA 1-gen-2022 Cacciotto, P.; Basciu, A.; Oliva, F.; Malloci, G.; Zacharias, M.; Ruggerone, P.; Vargiu, A. V. COMPUTATIONAL AND STRUCTURAL BIOTECHNOLOGY JOURNAL -
AB-DB: Force-Field parameters, MD trajectories, QM-based data, and Descriptors of Antimicrobials 1-gen-2022 Gervasoni, S.; Malloci, G.; Bosin, A.; Vargiu, A. V.; Zgurskaya, H. I.; Ruggerone, P. SCIENTIFIC DATA -
Bacterial efflux transporters’ polyspecificity – a gift and a curse? 1-gen-2021 Zgurskaya, Helen I.; Malloci, Giuliano; Chandar, Brinda; Vargiu, ATTILIO VITTORIO; Ruggerone, Paolo CURRENT OPINION IN MICROBIOLOGY -
Mechanistic Duality of Bacterial Efflux Substrates and Inhibitors: Example of Simple Substituted Cinnamoyl and Naphthyl Amides 1-gen-2021 D'Cunha, N.; Moniruzzaman, M.; Haynes, K.; Malloci, G.; Cooper, C. J.; Margiotta, E.; Vargiu, A. V.; Uddin, M. R.; Leus, I. V.; Cao, F.; Parks, J. M.; Rybenkov, V. V.; Ruggerone, P.; Zgurskaya, H. I.; Walker, J. K. ACS INFECTIOUS DISEASES -
Molecular insights into the Patched1 drug efflux inhibitory activity of panicein A hydroquinone: a computational study 1-gen-2021 Kovachka, S.; Malloci, G.; Vargiu, A. V.; Azoulay, S.; Mus-Veteau, I.; Ruggerone, P. PHYSICAL CHEMISTRY CHEMICAL PHYSICS -
Predictive rules of efflux inhibition and avoidance in Pseudomonas aeruginosa 1-gen-2021 Mehla, Jitender; Malloci, Giuliano; Mansbach, Rachael; López, Cesar A.; Tsivkovski, Ruslan; Haynes, Keith; Leus, Inga V.; Grindstaff, Sally B.; Cascella, Robert H.; D’Cunha, Napoleon; Herndon, Liam; Hengartner, Nicolas W.; Margiotta, Enrico; Atzori, Alessio; Vargiu, Attilio V.; Manrique, Pedro D.; Walker, John K.; Lomovskaya, Olga; Ruggerone, Paolo; Gnanakaran, S.; Rybenkov, Valentin V.; Zgurskaya, Helen I. MBIO -
Molecular interactions of carbapenem antibiotics with the multidrug efflux transporter acrb of escherichia coli 1-gen-2020 Atzori, A.; Malloci, G.; Cardamone, F.; Bosin, A.; Vargiu, A. V.; Ruggerone, P. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES -
Chlorpromazine and amitriptyline are substrates and inhibitors of the acrb multidrug efflux pump 1-gen-2020 Grimsey, E. M.; Fais, C.; Marshall, R. L.; Ricci, V.; Ciusa, M. L.; Stone, J. W.; Ivens, A.; Malloci, G.; Ruggerone, P.; Vargiu, A. V.; Piddock, L. J. V. MBIO -
The challenge of intracellular antibiotic accumulation, a function of fluoroquinolone influx versus bacterial efflux 1-gen-2020 Vergalli, J.; Atzori, A.; Pajovic, J.; Dumont, E.; Malloci, G.; Masi, M.; Vargiu, A. V.; Winterhalter, M.; Refregiers, M.; Ruggerone, P.; Pages, J. -M. COMMUNICATIONS BIOLOGY -
Perturbed structural dynamics underlie inhibition and altered efflux of the multidrug resistance pump AcrB 1-gen-2020 Fais, Chiara; Malloci, Giuliano; Ruggerone, Paolo; Vargiu, ATTILIO VITTORIO NATURE COMMUNICATIONS -
Cryo-EM structure and molecular dynamics analysis of the fluoroquinolone resistant mutant of the AcrB transporter from salmonella 1-gen-2020 Johnson, R. M.; Fais, C.; Parmar, M.; Cheruvara, H.; Marshall, R. L.; Hesketh, S. J.; Feasey, M. C.; Ruggerone, P.; Vargiu, A. V.; Postis, V. L. G.; Muench, S. P.; Bavro, V. N. MICROORGANISMS -
Binding and Transport of Carboxylated Drugs by the Multidrug Transporter AcrB 1-gen-2020 Tam, Hk; Malviya, Vn; Foong, We; Herrmann, A; Malloci, G; Ruggerone, P; Vargiu, Av; Pos, Km JOURNAL OF MOLECULAR BIOLOGY -
Relevance of Ebola virus VP35 homo-dimerization on the type I interferon cascade inhibition 1-gen-2019 Di Palma, Francesco; Daino, Gian Luca; Ramaswamy, Venkata Krishnan; Corona, Angela; Frau, Aldo; Fanunza, Elisa; Vargiu, Attilio V; Tramontano, Enzo; Ruggerone, Paolo ANTIVIRAL CHEMISTRY & CHEMOTHERAPY -
Identification and characterization of carbapenem binding sites within the RND-transporter AcrB 1-gen-2019 Atzori, Alessio; Malviya, Viveka N.; Malloci, Giuliano; Dreier, Jürg; Pos, Klaas M.; Vargiu, Attilio V.; Ruggerone, Paolo BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES -
Molecular Interactions of Cephalosporins with the Deep Binding Pocket of the RND Transporter AcrB 1-gen-2019 Atzori, Alessio; Malloci, Giuliano; Dahyabhai Prajapati, Jigneshkumar; Basciu, Andrea; Bosin, Andrea; Kleinekathöfer, Ulrich; Dreier, Jürg; Vargiu, Attilio V.; Ruggerone, Paolo JOURNAL OF PHYSICAL CHEMISTRY. B, CONDENSED MATTER, MATERIALS, SURFACES, INTERFACES & BIOPHYSICAL -
Molecular basis for the different interactions of congeneric substrates with the polyspecific transporter AcrB 1-gen-2019 Malvacio, Ivana; Rosa, Buonfiglio; Noemi, D'Atanasio; Serra, Giovanni; Bosin, Andrea; Francesco Paolo Di Giorgio, ; Ruggerone, Paolo; Rosella, Ombrato; Vargiu, ATTILIO VITTORIO BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES -
Computer simulations of the activity of RND efflux pumps 1-gen-2018 Vargiu, Attilio Vittorio; Ramaswamy, Venkata Krishnan; Malloci, Giuliano; Malvacio, Ivana; Atzori, Alessio; Ruggerone, Paolo RESEARCH IN MICROBIOLOGY -
A New Critical Conformational Determinant of Multidrug Efflux by an MFS Transporter 1-gen-2018 Zomot, Elia; Yardeni, Eliane Hadas; Vargiu, Attilio Vittorio; Tam, Heng-Keat; Malloci, Giuliano; Ramaswamy, Venkata Krishnan; Perach, Michal; Ruggerone, Paolo; Pos, Klaas Martinus; Bibi, Eitan JOURNAL OF MOLECULAR BIOLOGY -
Insights into the homo-oligomerization properties of N-terminal coiled-coil domain of Ebola virus VP35 protein 1-gen-2018 Ramaswamy, VENKATA KRISHNAN; DI PALMA, Francesco; Vargiu, Attilio V.; Corona, Angela; Piano, Dario; Ruggerone, Paolo; Zinzula, Luca; Tramontano, Enzo VIRUS RESEARCH -
Mostrati risultati da 1 a 20 di 150
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