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Titolo Data di pubblicazione Autore(i) Rivista Editore
COR758, a negative allosteric modulator of GABAB receptors 2021 Porcu, A.; Mostallino, R.; Serra, V.; Melis, M.; Sogos, V.; Beggiato, S.; Ferraro, L.; Manetti, F....; Gianibbi, B.; Bettler, B.; Corelli, F.; Mugnaini, C.; Castelli, M. P. NEUROPHARMACOLOGY
Repeated exposure to JWH-018 induces adaptive changes in the mesolimbic and mesocortical dopamine pathways, glial cells alteration and behavioural correlates 2021 Pintori, Nicholas; Castelli, Maria Paola; Miliano, Cristina; Simola, Nicola; Fadda, Paola; Fattor...e, Liana; Scherma, Maria; Ennas, Maria Grazia; Mostallino, Rafaela; Flore, Giovanna; De Felice, Marta; Sagheddu, Claudia; Pistis, Marco; Di Chiara, Gaetano; De Luca, Maria Antonietta BRITISH JOURNAL OF PHARMACOLOGY
Human neuronal cell lines as an in vitro toxicological tool for the evaluation of novel psychoactive substances 2021 Sogos, V.; Caria, P.; Porcedda, C.; Mostallino, R.; Piras, F.; Miliano, C.; De Luca, M. A.; Caste...lli, M. P. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
Structure optimization of positive allosteric modulators of GABAB receptors led to the unexpected discovery of antagonists/potential negative allosteric modulators 2020 Mugnaini, C.; Brizzi, A.; Mostallino, R.; Castelli, M. P.; Corelli, F. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
The GABAB receptor positive allosteric modulator COR659: in vitro metabolism, in vivo pharmacokinetics in rats, synthesis and pharmacological characterization of metabolically protected derivatives 2020 Ferlenghi, Francesca; Maccioni, Paola; Mugnaini, Claudia; Brizzi, Antonella; Fara, Federica; Most...allino, Rafaela; Castelli, Maria Paola; Colombo, Giancarlo; Mor, Marco; Vacondio, Federica; Corelli, Federico EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES
Sex and gender differences in the effects of novel psychoactive substances 2020 Fattore, Liana; Marti, Matteo; Mostallino, Rafaela; Castelli, Maria Paola BRAIN SCIENCES
Neurochemical and Behavioral Profiling in Male and Female Rats of the Psychedelic Agent 25I-NBOMe 2019 Miliano, Cristina; Marti, Matteo; Pintori, Nicholas; Castelli, Maria Paola; Tirri, Micaela; Arfè,... Raffaella; De Luca, Maria Antonietta FRONTIERS IN PHARMACOLOGY
Impaired brain endocannabinoid tone in the activity-based model of anorexia nervosa 2019 Collu, R.; Scherma, M.; Piscitelli, F.; Giunti, E.; Satta, V.; Castelli, M. P.; Verde, R.; Fratta..., W.; Bisogno, T.; Fadda, P. INTERNATIONAL JOURNAL OF EATING DISORDERS
Predisposition to alcohol drinking and alcohol consumption alter expression of calcitonin gene-related peptide, neuropeptide Y, and microglia in bed nucleus of stria terminalis in a subnucleus-specific manner 2019 Rossetti, Ilaria; Zambusi, Laura; Maccioni, Paola; Sau, Roberta; Provini, Luciano; Castelli, Mari...a Paola; Gonciarz, Krzysztof; Colombo, Giancarlo; Morara, Stefano FRONTIERS IN CELLULAR NEUROSCIENCE
Limited access to a high fat diet alters endocannabinoid tone in female rats 2018 Satta, Valentina; Scherma, Maria; Piscitelli, Fabiana; Usai, Paolo; Castelli, M Paola; Bisogno, T...iziana; Fratta, Walter; Fadda, Paola FRONTIERS IN NEUROSCIENCE
In vitro functional characterization of GET73 as possible negative allosteric modulator of metabotropic glutamate receptor 5 2018 Beggiato, Sarah; Borelli, Andrea C.; Tomasini, Maria C.; Castelli, MARIA PAOLA; Pintori, Nicholas...; Cacciaglia, Roberto; Loche, Antonella; Ferraro, LUCA NICOLA FRONTIERS IN PHARMACOLOGY
Rimonabant, a potent CB1 cannabinoid receptor antagonist, is a G alpha(i/o) protein inhibitor 2018 Porcu, Alessandra; Melis, Miriam; Turecek, Rostislav; Ullrich, Celine; Mocci, Ignazia; Bettler, B...ernhard; Luigi Gessa, Gian; Castelli, MARIA PAOLA NEUROPHARMACOLOGY
Cannabis and the Use of Amphetamine-Like Substances 2017 Porcu, Alessandra; Castelli, MARIA PAOLA Elsevier
Suppressing effect of saikosaponin A, an active ingredient of Bupleurum falcatum, on chocolate self-administration and reinstatement of chocolate seeking in rats 2017 Lorrai, Irene; Maccioni, Paola; Carai, Mauro Antonio Maria; Capra, Alessandro; Castelli, Maria Pa...ola; Riva, Antonella; Morazzoni, Paolo; Gessa, Gian Luigi; Colombo, Giancarlo NEUROSCIENCE LETTERS
Native CB1 receptor affinity, intrinsic activity and accumbens shell dopamine stimulant properties of third generation SPICE/K2 cannabinoids: BB-22, 5F-PB-22, 5F-AKB-48 and STS-135 2016 De Luca, MA; Castelli, MP; Loi, B; Porcu, A; Martorelli, M; Miliano, C; Kellett, K; Davidson, C; ...Stair, JL; Schifano, F; Di Chiara, G NEUROPHARMACOLOGY
α2A adrenergic receptors highly expressed in mesoprefrontal dopamine neurons 2016 Castelli, MARIA PAOLA; Spiga, Saturnino; Perra, Andrea; Madeddu, Camilla; Mulas, Giovanna; Ennas,... MARIA GRAZIA; Gessa, Gl NEUROSCIENCE
Influence of caffeine on 3,4-methylenedioxymethamphetamine-induced dopaminergic neuron degeneration and neuroinflammation is age-dependent 2016 Frau, Lucia; Costa, Giulia; Porceddu, Pier Francesca; Khairnar, Amit; Castelli, Maria Paola; Enna...s, Maria Grazia; Madeddu, Camilla; Wardas, Jadwiga; Morelli, Micaela JOURNAL OF NEUROCHEMISTRY
Distribution and localization of the GABAB receptor 2016 Castelli, MARIA PAOLA; Gessa, Gian Luigi Springer
In vitro and in vivo pharmacological characterization of SSD114, a novel GABAB positive allosteric modulator 2016 Porcu, Alessandra; Lobina, Carla; Giunta, Daniela; Solinas, Maurizio; Mugnaini, Claudia; Castelli..., MARIA PAOLA EUROPEAN JOURNAL OF PHARMACOLOGY
Male and Female Rats Differ in Brain Cannabinoid CB1 Receptor Density and Function and in Behavioural Traits Predisposing To Drug Addiction: Effect of Ovarian Hormones. 2014 Castelli MP; Fadda P; Casu A; Spano MS; Casti A; Fratta W; Fattore L CURRENT PHARMACEUTICAL DESIGN

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