Micaela Morelli

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In utero exposure to dexamethasone causes a persistent and age-dependent exacerbation of the neurotoxic effects and glia activation induced by MDMA in dopaminergic brain regions of C57BL/6J mice 2021 Costa, G.; Spulber, S.; Paci, E.; Casu, M. A.; Ceccatelli, S.; Simola, N.; Morelli, M. NEUROTOXICOLOGY
Increased emissions of 50-kHz ultrasonic vocalizations in hemiparkinsonian rats repeatedly treated with dopaminomimetic drugs: A potential preclinical model for studying the affective properties of dopamine replacement therapy in Parkinson's disease 2021 Simola, Nicola; Serra, Marcello; Marongiu, Jacopo; Costa, Giulia; Morelli, Micaela PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY
Activation of Antioxidant and Proteolytic Pathways in the Nigrostriatal Dopaminergic System After 3,4-Methylenedioxymethamphetamine Administration: Sex-Related Differences 2021 Costa, G.; Caputi, F. F.; Serra, M.; Simola, N.; Rullo, L.; Stamatakos, S.; Sanna, F.; Germain, M....; Martinoli, M. -G.; Candeletti, S.; Morelli, M.; Romualdi, P. FRONTIERS IN PHARMACOLOGY
Gender Differences in Neurodegeneration, Neuroinflammation and Na+-Ca2+ Exchangers in the Female A53T Transgenic Mouse Model of Parkinson’s Disease 2020 Costa, Giulia; Sisalli, Maria Jose; Simola, Nicola; Della Notte, Salvatore; Casu, Maria Antoniett...a; Serra, Marcello; Pinna, Annalisa; Feliciello, Antonio; Annunziato, Lucio; Scorziello, Antonella; Morelli, Micaela FRONTIERS IN AGING NEUROSCIENCE
Influence of dopamine transmission in the medial prefrontal cortex and dorsal striatum on the emission of 50-kHz ultrasonic vocalizations in rats treated with amphetamine: Effects on drug-stimulated and conditioned calls 2020 Costa, Giulia; Serra, Marcello; Marongiu, Jacopo; Morelli, Micaela; Simola, Nicola PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY
Genetic variants of TAS2R38 bitter taste receptor associate with distinct gut microbiota traits in Parkinson's disease: A pilot study 2020 Vascellari, Sarah; Melis, Melania; Cossu, Giovanni; Melis, Marta; Serra, Alessandra; Palmas, Vane...ssa; Perra, Daniela; Oppo, Valentina; Fiorini, Michele; Cusano, Roberto; Morelli, Micaela; Manzin, Aldo; Barbarossa, Iole Tomassini INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
Gut Microbiota and Metabolome Alterations Associated with Parkinson’s Disease 2020 Vascellari, Sarah; Palmas, Vanessa; Melis, Marta; Pisanu, Silvia; Cusano, Roberto; Uva, Paolo; Pe...rra, Daniela; Madau, Veronica; Sarchioto, Marianna; Oppo, Valentina; Simola, Nicola; Morelli, Micaela; Santoru, Maria Laura; Atzori, Luigi; Melis, Maurizio; Cossu, Giovanni; Manzin, Aldo MSYSTEMS
Combined administration of dopaminergic and nondopaminergic drugs reverses neuroinflammation in a rat model of Parkinson’s disease 2019 Costa, G; Serra, M.; Morelli, M.; Pinna, A JOURNAL OF NEUROCHEMISTRY
Neuroinflammation and activation of Zif-268 in dyskinetic 6-OHDA-lesioned rats is counteracted by association of a 5-HT1A/1B receptor agonist and an A2A receptor antagonist 2019 Pinna, A; Costa, G; Serra, M.; Morelli, M MOVEMENT DISORDERS
Odor identification performance in idiopathic Parkinson’s disease is associated with gender and the genetic variability of the olfactory binding protein 2019 Melis, M.; Sollai, G.; Masala, C.; Pisanu, C.; Cossu, G.; Melis, M.; Sarchioto, M.; Oppo, V.; Mor...elli, M.; Crnjar, R.; Hummel, T.; Barbarossa, I. CHEMICAL SENSES
Lack of Rhes Increases MDMA-Induced Neuroinflammation and Dopamine Neuron Degeneration: Role of Gender and Age 2019 Costa, Giulia; Porceddu, Pier Francesca; Serra, Marcello; Casu, Maria Antonietta; Schiano, Valent...ina; Napolitano, Francesco; Pinna, Annalisa; Usiello, Alessandro; Morelli, Micaela INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
Neurochemical and neurotoxic effects of MDMA (Ecstasy) and caffeine after chronic combined administration in mice 2018 Górska, Anna Maria; Kamińska, Katarzyna; Wawrzczak-Bargieła, Agnieszka; Costa, Giulia; Morelli, M...icaela; Przewłocki, Ryszard; Kreiner, Grzegorz; Gołembiowska, Krystyna NEUROTOXICITY RESEARCH
6-n-propylthiouracil taste disruption and TAS2R38 nontasting form in Parkinson's disease 2018 Cossu, Giovanni; Melis, Melania; Sarchioto, Marianna; Melis, Marta; Melis, Maurizio; Morelli, Mic...aela; Tomassini Barbarossa, Iole MOVEMENT DISORDERS
NCX1 and NCX3 as potential factors contributing to neurodegeneration and neuroinflammation in the A53T transgenic mouse model of Parkinson's Disease 2018 Sirabella, Rossana; Sisalli, Maria Josè; Costa, Giulia; Omura, Katia; Ianniello, Gaetano; Pinna, ...Annalisa; Morelli, Micaela; Di Renzo, Gianfranco Maria; Annunziato, Lucio; Scorziello, Antonella CELL DEATH & DISEASE
Modulation of rat 50-kHz ultrasonic vocalizations by glucocorticoid signaling: possible relevance to reward and motivation 2018 Simola, Nicola; Paci, Elena; Serra, Marcello; Costa, Giulia; Morelli, Micaela INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY
Role of adenosine A2A receptors in motor control: relevance to Parkinson’s disease and dyskinesia 2018 Pinna, Annalisa; Serra, Marcello; Morelli, Micaela; Simola, Nicola JOURNAL OF NEURAL TRANSMISSION
Rhes counteracts dopamine neuron degeneration and neuroinflammation depending on gender and age 2018 Costa, Giulia; Pinna, Annalisa; Porceddu, Pier Francesca; Casu, Maria Antonietta; Di Maio, Anna; ...Napolitano, Francesco; Usiello, Alessandro; Morelli, Micaela FRONTIERS IN AGING NEUROSCIENCE
Repeated Administration of 3,4-Methylenedioxymethamphetamine (MDMA) Elevates the Levels of Neuronal Nitric Oxide Synthase in the Nigrostriatal System: Possible Relevance to Neurotoxicity 2018 Costa, Giulia; Morelli, Micaela; Simola, Nicola NEUROTOXICITY RESEARCH
A preclinical study on the combined effects of repeated eltoprazine and preladenant treatment for alleviating L-DOPA-induced dyskinesia in Parkinson's disease 2017 Ko, Wai Kin D.; Li, Qin; Cheng, Long Yun; Morelli, Micaela; Carta, Manolo; Bezard, Erwan EUROPEAN JOURNAL OF PHARMACOLOGY
Progression and Persistence of Neurotoxicity Induced by MDMA in Dopaminergic Regions of the Mouse Brain and Association with Noradrenergic, GABAergic, and Serotonergic Damage 2017 Costa, Giulia; Morelli, Micaela; Simola, Nicola NEUROTOXICITY RESEARCH
Decreased Rhes mRNA levels in the brain of patients with Parkinson’s disease and MPTP-treated macaques 2017 Napolitano, Francesco; Warren, Emily Booth; Migliarini, Sara; Punzo, Daniela; Errico, Francesco; ...Li, Qin; Thiolat, Marie-Laure; Vescovi, Angelo Luigi; Calabresi, Paolo; Bezard, Erwan; Morelli, Micaela; Konradi, Christine; Pasqualetti, Massimo; Usiello, Alessandro PLOS ONE
Role of Adenosine in the basal Ganglia 2017 Morelli, M.; Simola, N.; Popoli, P.; Carta, A.R. Elsevier
Amphetamine-related drugs neurotoxicity in humans and in experimental animals: Main mechanisms 2017 Moratalla, Rosario; Khairnar, Amit; Simola, Nicola; Granado, Noelia; García-Montes, Jose Ruben; P...orceddu, Pier Francesca; Tizabi, Yousef; Costa, Giulia; Morelli, Micaela PROGRESS IN NEUROBIOLOGY
Gender-dependent behavioral and biochemical differences in the A53T genetic mouse model of Parkinson’s disease 2016 Costa, G.; Sisalli, M. J.; Contu, L.; Scorziello, A.; Morelli, M. MOVEMENT DISORDERS
The small GTP-binding protein Rhes influences midbrain dopaminergic neurons: Behavioral and biochemical studies 2016 Pinna, A.; Napolitano, F.; Costa, G.; Porceddu, P. F.; Contu, L.; Wardas, J.; Casu, M. A.; Usiell...o, A.; Morelli, M. MOVEMENT DISORDERS
The Small GTP-Binding Protein Rhes Influences Nigrostriatal-Dependent Motor Behavior During Aging 2016 Pinna, A; Napolitano, F; Pelosi, B; Di Maio, A; Wardas, J; Casu, Ma; Costa, G; Migliarini, S; Cal...abresi, P; Pasqualetti, M; Morelli, M; Usiello, A MOVEMENT DISORDERS
Influence of caffeine on 3,4-methylenedioxymethamphetamine-induced dopaminergic neuron degeneration and neuroinflammation is age-dependent 2016 Frau, Lucia; Costa, Giulia; Porceddu, Pier Francesca; Khairnar, Amit; Castelli, Maria Paola; Enna...s, Maria Grazia; Madeddu, Camilla; Wardas, Jadwiga; Morelli, Micaela JOURNAL OF NEUROCHEMISTRY
Novel (Hetero)arylalkenyl propargylamine compounds are protective in toxin-induced models of Parkinson's disease 2016 Baranyi, M; Porceddu, Pf; Goloncser, F; Kulcsar, S; Otrokocsi, L; Kittel, A; Pinna, A; Frau, L; H...uleatt, Pb.; Khoo, Ml; Chai, Cll.; Dunkel, P; Matyus, P; Morelli, M; Sperlagh, B MOLECULAR NEURODEGENERATION
Metformin prevented dopaminergic neurotoxicity induced by 3,4-Methylenedioxymethamphetamine administration 2016 Porceddu, PF; Ishola, IO; Contu, L; Morelli, M NEUROTOXICITY RESEARCH
Activation of adenosine A2A receptors suppresses the emission of pro-social and drug-stimulated 50-kHz ultrasonic vocalizations in rats: possible relevance to reward and motivation 2016 Simola, N; Costa, G; Morelli, M PSYCHOPHARMACOLOGY
Effect of crowding, temperature and age on glia activation and dopaminergic neurotoxicity induced by MDMA in the mouse brain 2016 Frau, Lucia; Simola, Nicola; Porceddu, PIER FRANCESCA; Morelli, Micaela NEUROTOXICOLOGY
Methylxanthines and drug dependence: interactions and toxicity 2016 Costa, Giulia; Morelli, Micaela; Simola, Nicola Elsevier
Antidyskinetic effect of A2A and 5HT1A/1B receptor ligands in two animal models of Parkinson's disease 2016 Pinna, A; Ko, WKD; Costa, G; Tronci, E; Fidalgo, C; Simola, N; Li, Q; Tabrizi, MA; Bezard, E; Car...ta, M; Morelli, M MOVEMENT DISORDERS
Repeated amphetamine administration and long-term effects on 50-kHz ultrasonic vocalizations: possible relevance to the motivational and dopamine-stimulating properties of the drug 2015 Simola, N; Morelli, M EUROPEAN NEUROPSYCHOPHARMACOLOGY
Pathophysiology of L-dopa-induced motor and non-motor complications in Parkinson's disease 2015 Bastide, MF; Meissner, WG; Picconi, B; Fasano, S; Fernagut, PO; Feyder, M; Francardo, V; Alcacer,... C; Ding, YM; Brambilla, R; Fisone, G; Stoessl, AJ; Bourdenx, M; Engeln, M; Navailles, S; De Deurwaerdere, P; Ko, WKD; Simola, N; Morelli, M; Groc, L; Rodriguez, MC; Gurevich, EV; Quik, M; Morari, M; Mellone, M; Gardoni, F; Tronci, E; Guehl, D; Tison, F; Crossman, AR; Kang, UJ; Steece-Collier, K; Fox, S; Carta, M; Cenci, AM; Bezard, E PROGRESS IN NEUROBIOLOGY
Preface [ to The Adenosinergic System. A Non-Dopaminergic Target in Parkinson’s Disease] 2015 Morelli, Micaela; Simola, Nicola; Wardas, J. Springer International
Involvement of Glutamate NMDA Receptors in the Acute, Long-Term, and Conditioned Effects of Amphetamine on Rat 50kHz Ultrasonic Vocalizations 2015 COSTA G; MORELLI M; SIMOLA N INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY
Antiparkinsonian actions and interactions of adenosine antagonists 2014 Morelli, M.; Costa, G.; Pinna, A. PURINERGIC SIGNALLING
Antagonism of Adenosine A1 or A2A Receptors Amplifies the Effects of 3,4-Methylendioxymethamphetamine (MDMA) on Glial Activation in the Mouse Brain: Relevance to Caffeine-MDMA Interactions 2014 KHAIRNAR A; FRAU L; PLUMITALLO A; MORELLI M; SIMOLA N JOURNAL OF CAFFEINE RESEARCH
Elevation of striatal urate in experimental models of Parkinson's disease: a compensatory mechanism triggered by dopaminergic nigrostriatal degeneration? 2014 DE LUCA M; CAULI O; MORELLI M; SIMOLA N. JOURNAL OF NEUROCHEMISTRY
Direct and long-lasting effects elicited by repeated drug administration on 50-kHz ultrasonic vocalizations are regulated differently: Implications for the study of the affective properties of drugs of abuse 2014 SIMOLA N; FRAU L; PLUMITALLO A; MORELLI M INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY
A critical evaluation of behavioral rodent models of motor impairment used for screening of antiparkinsonian activity: The case of adenosine A2A receptor antagonists 2014 PINNA A; MORELLI M NEUROTOXICITY RESEARCH
MDMA administration during adolescence exacerbates MPTP-induced cognitive impairment and neuroinflammation in the hippocampus and prefrontal cortex 2014 COSTA G; SIMOLA N; MORELLI M PSYCHOPHARMACOLOGY
Effect of memantine on L-DOPA-induced dyskinesia in the 6-OHDA-lesioned rat model of Parkinson's disease. 2014 TRONCI E; FIDALGO C; ZIANNI E; COLLU M; STANCAMPIANO R; MORELLI M; GARDONI F; CARTA M NEUROSCIENCE
Dyskinesia in Parkinson's disease: mechanisms and current non-pharmacological interventions 2014 HEUMANN R; MORATALLA R; HERRERO M T; CHAKRABARTY K; DRUCKER-COLIN R; GARCIA-MONTES J R; SIMOLA N;... MORELLI M JOURNAL OF NEUROCHEMISTRY
Protective Agents in Parkinson's Disease: Caffeine and Adenosine A2A Receptor Antagonists 2014 SIMOLA N; PINNA A; FRAU L; MORELLI M Springer
Contribution of Caffeine to the Psychostimulant, Neuroinflammatory and Neurotoxic Effects of Amphetamine-Related Drugs 2013 FRAU L; SIMOLA N; MORELLI M JOURNAL OF CAFFEINE RESEARCH
MPTP-induced dopamine neuron degeneration and glia activation is potentiated in MDMA pretreated mice 2013 COSTA G; FRAU L; WARDAS J; PINNA A; PLUMITALLO A; MORELLI M MOVEMENT DISORDERS
Role of movement in long-term basal ganglia changes: implications for abnormal motor responses 2013 SIMOLA N; MORELLI M; FRAZZITTA G; FRAU L FRONTIERS IN COMPUTATIONAL NEUROSCIENCE
Symptomatic and Neuroprotective Effects of A2A Receptor Antagonists in Parkinson’s Disease 2013 PINNA A; SIMOLA N; FRAU L; MORELLI M Springer Science

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