Titolo:  Synthesis and Biological Evaluation of a Novel Series of Bis-Salicylaldehydes as Mushroom Tyrosinase Inhibitors
Autori: 
Data di pubblicazione:  2010
Rivista: 
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS  
Abstract:  A series of novel bis-salicylaldehydes were synthesised and evaluated as tyrosinase inhibitors using a tyrosinase-dependent L-DOPA oxidation assay. The bis-salicylaldehydes exhibited greater inhibitory activity than salicylaldehyde. Our data suggests that these novel compounds may serve as a structural template for the design and development of novel tyrosinase inhibitors.
Handle:  http://hdl.handle.net/11584/106776
Tipologia: 1.1 Articolo in rivista

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