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Professor
ALESSANDRA SERRA (Tit.)
MARCO LUSSU
Period
First Semester 
Teaching style
Convenzionale 
Lingua Insegnamento
 



Informazioni aggiuntive

Course Curriculum CFU Length(h)
[40/49]  IMAGING AND RADIOTHERAPY TECHNIQUES [49/00 - Ord. 2020]  PERCORSO COMUNE 7 56

Objectives

Acquiring integrated knowledge and understanding of the scientific and technical fundamentals of nuclear technologies.
The student will demonstrate and exhibit comprehension of the studies and procedures performed in a Nuclear Medicine clinic, including standards of ethics governing pharmacy practice (Knowledge of concepts of radiopharmacy; radionuclide production and radiolabeling; interpret the mechanism of localization of various radiopharmaceuticals; cite quality control tests of various radiopharmaceuticals; explain the legislation related to radiopharmaceuticals).
To develop students’ ability in becoming more proficient in care of patients in a team-focused healthcare environment.
Students will develop verbal and written communication skills to effectively interact within a healthcare setting;
Demonstrate a working knowledge of nuclear medicine procedures and techniques (diagnostic and therapeutic routine procedures).Practical application of theory and skill to achieve clinical competency in Nuclear Medicine procedures, patient care, instrument quality control, computer analysis and radiopharmacy practices. Positron Emission Tomography (PET), Computed Tomography (CT),
Practical general training and experiences in the workplace

Prerequisites

Knowledge of basic concepts of nuclear physics (formation of radionuclides and decay modes), physics of nuclear medical equipment, concepts of chemistry, human physiology and anatomy

Contents

Radiopharmacy (8 hours)
Properties of the radionuclide of interest in diagnostic nuclear medicine. Physical and chemical characteristics of Tc-99m.
General synthetic radiolabeling methods
Preparation of radiopharmaceuticals used for diagnostic purpose including the purpose of each. Quality control by Instant thin layer chromatography (ITLC) for estimation of the radiochemical purity.
Preparation and production of radiopharmaceuticals in positron emission tomography (PET). Quality control procedures for Positron Emission Tomography radiopharmaceuticals.

Nuclear Medicine Therapy (8hours)
The basic principles of targeted radionuclide therapy.
radiopharmaceuticals labelled with beta emitting radionuclides used in radionuclide therapy.
radiopharmaceuticals for benign or malignant thyroid diseases
radiopharmaceuticals for bone pain palliation
radiopharmaceuticals for primary cancer treatment peptide receptor radionuclide therapy in neuroendocrine tumors radioimmunotherapy
radiopharmaceuticals for radiosynoviorthesis.

RADIOPHARMACY AND NUCLEAR MEDICINE TECHNIQUES (32 HOURS)
OBJECTIVES: to acquire the theoretical knowledge and properties of technical language regarding the paths, regulations, equipment and radiopharmaceuticals used in nuclear medicine. Learn the technical aspects related to the different scintigraphic imaging pathways and protocols.

- Introduction to Nuclear Medicine and the Patient pathway
-Internal regulations on radiation protection and individual protection devices

- Radiopharmacy Regulations: Standards of Good Preparation and Pharmacopoeia
Quality Assurance System in Nuclear Medicine
- Chemistry of Technetium - Radioisotopes in Conventional Nuclear Medicine and Pet

- Technetium Generator - Radiopharmaceuticals labeling and fractionation of ready-to-use radiopharmaceuticals - Quality controls on the technetium generator and radiopharmaceutical preparations

- Gammacamera structure, PET tomograph and radioiodine detection probe and related daily quality checks



Imaging Protocols Using Gamma Camera, Pet Tomograph and hybrid machines

Technical aspects of the following nuclear medical investigations:
- Scintigraphies with sodium pertechnetate (thyroid, sequential salivary glands, Meckel's diverticulum research, esophageal transit)
- Bone scintigraphy, Polyphasic Bone, Sentinel Lymph Node Research and Roll
- Sequential Renal Scintigraphy, Static Renal Scintigraphy,
- Cerebral Perfusional Scintigraphy and Cerebral Receptor Scintigraphy,
- Perfusional Lung Scintigraphy, Ventilatory Pulmonary Scintigraphy,
- Scintigraphy with labeled leukocytes
- Parathyroid scintigraphy, Myocardial scintigraphy, Scintigraphy with marked red blood cells
- Global Body Receptor Scintigraphy with Indium 111,
- Total body scan with I131-sodium iodide
- Medullary Adrenal Scintigraphy; Cortical Adrenal Scintigraphy, Scintigraphy with Gallium Citrate.
maging protocols Using PET and PET / CT in oncology, neurology and cardiology.

Teaching Methods

Practical application of theory and skill to achieve clinical competency in Nuclear Medicine procedures, patient care, instrument quality control, computer analysis and radiopharmacy practices. Positron Emission Tomography (PET), Computed Tomography (CT),
Practical general training and experiences in the workplace

Verification of learning

Classroom lectures (students will be given the teaching material used during the lessons).
final exam
Oral verification qualitative assessment: acquisition of notions, concepts, knowledge, presentation skills.
Written and oral tests examination to verify and evaluate the student’s knowledge.
Evaluation is expressed on a scale 0-30 and it is calculated as the average of the votes of each module.

Texts

Classroom lectures (students will be given the teaching material used during the lessons).
Recommended texts:
Nuclear Medicine Textbook
Methodology and Clinical Applications.
Duccio Volterrani, Paola Anna Erba, Ignasi Carrio, H. William Strauss, Giuliano Mariani.
Springer

More Information

Classroom lectures (students will be given the teaching material used during the lessons).

Questionnaire and social

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