Teachings

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Professor
GIORGIO LA NASA (Tit.)
GIOVANNI CAOCCI
ELENA MASSA
MARIO SCARTOZZI
Period
Second Semester 
Teaching style
Convenzionale 
Lingua Insegnamento
 



Informazioni aggiuntive

Course Curriculum CFU Length(h)
[40/39]  MEDICINE AND SURGERY [39/00 - Ord. 2013]  PERCORSO COMUNE 8 68

Objectives

Students shall be able to evaluate patients’ health status from the preventive, diagnostic, therapeutic and rehabilitative point of view, and integrate the contributions of systematic pathology and specialized medicine in a unitary vision of an individual suffering from a specific disease.
During the lessons, students will be provided with a rational basis of the pathogenetic mechanisms and their use in diagnostic and therapy, and also with the connection between Hematology and the other branches of clinical Medicine. These aims will be partly reached with formal teaching and partly with the direct examination of clinical cases, in the presence of the patient or through clinical records.
Educational objectives of Oncology:
Learning of knowledge that, starting from the basic biological and epidemiological aspects, will allow the acquisition of the clinical and social impact of Oncology. This involves knowledge of cancer epidemiology and risk factors, the characteristics of the major cancers in different stages of disease, the phases of a clinical protocol, the side effects of anti-neoplastic therapies, supportive care. The course will also give the essential knowledge on the therapeutic strategies of the most frequent tumors. Particular emphasis will be given to the need for a multidisciplinary approach both in the diagnostic in that the therapeutic phase of the main cancers. Through the practical lessons through the analysis of clinical cases the students will be provided with the basic knowledge essential to evaluate the patient clinical condition as well as the tumor staging and the main factors driving the choice of therapy. Moreover, they will gain direct experience of the main toxicity of chemotherapy and ways to treat and prevent them.

Prerequisites

Course attendance as established by the Degree Course guidelines.

Contents

Hemopoiesis. Hyporegenerative Anemias. Thalassemia syndromes. Hemolytic Anemias. Bone Marrow Aplasia. Myelodisplasias. Acute Leukemias. Chronic Myeloid Leukemia. Ph- Chronic Myeloproliferative Neoplasias. Hodgkin’s Lymphoma. Non-Hodgkin’s Lymphoma. Chronic Lymphatic Leukemia. Monoclonal Gammopathies. Multiple Myeloma. Stem Cells and logical transplant principles. CID. Thrombocytopenias. Thrombotic Microangiopathies. Problem approach. Urgencies and emergencies in hematology. Clinical cases.

Epidemiology of solid tumors: risk factors. Primary and secondary prevention of cancer. Chemoprevention of cancer. Principles of cell proliferation and drug-resistance. Principles of tumor dissemination and metastatization. Tumor staging. General prognostic and predictive factors of cancer. Antiproliferative drugs: class, mechanism of action and toxicity. Targeted agents. Chemotherapy indications: neoadjuvant, adjuvant, curative, palliative setting. Principles regulating controlled clinical trial. Assessment of therapeutic response. Follow-up in Medical Oncology. Breast cancer. Lung cancer. Colorectal cancer. Gynecological Malignancies (cancer of the endometrium, carcinoma of the cervix). Prostate cancer. Neoplasms of the head and neck. Oncological emergencies. Pathogenesi of pain in oncology and treatment. Geriatric Oncology: multidimensional geriatric assessment. Supportive therapies in oncology. Palliative care. Cancer cachexia.

1- Epidemiology of Cancer and cancer statistics
2 - Primary and secondary prevention, screening programs active and their characteristics
3 - General concepts of staging, TNM
4 - Guidance to medical treatment / surgery / radiotherapy
5 - General concepts on how the overall assessment of the patient with cancer
6 - General Concepts of chemotherapy, combination chemotherapy, single-agent chemotherapy, neo-adjuvant chemotherapy, adjuvant, palliative.
7 – Evalutation’s Criteria of response to chemotherapy.
8 - Main side effects of chemotherapy drugs
9-General concepts of clinical trials, experimental trials in vitro, in vivo, studies of phase I, II, III, IV.
10 - Geriatric Oncology
11 - Epidemiology, risk factors, diagnosis, pathology, staging, treatment of the following cancers:
- Breast cancer, lung cancer, colorectal cancer, ovarian, cervix and uterine carncer, head and neck cancer, prostate cancer, bladder cancer, seminomas.

Teaching Methods

Theoretical lessons accompanied by an audio-video support of Power Point files and films. Practice (visits and participation in inpatient hospital services on patients) in the Bone Marrow Transplantation Center – Hematology Department of the Hospital “R. Binaghi”.
Department of Medical Oncology, AOU Cagliari (Ambulatory, out-patient hospital services, Inpatient hospital services).
Theoretical lessons accompanied by an audio-video support of Power Point files and films. Practice (visits and participation in inpatient hospital services on patients) (AOU of Cagliari, Medical Oncology Department, Policlinico Universitario, Monserrato.

Verification of learning

Oral; Students will be evaluated by all the lecturers collectively.

Texts

“MANUALE DI MALATTIE DEL SANGUE" Bosi A., De Stefano V., Di Raimondo F., La Nasa G. Ed. ELSEVIER.

More Information

Contact information
Prof. Giorgio La Nasa
CTMO-EMATOLOGIA – Hospital: P.O Businco Via Jenner Cagliari
giorgiolanasa@medicina.unica.it
Prof. Giovanni Caocci
CTMO-EMATOLOGIA – Hospital: P.O Businco Via Jenner Cagliari
giovanni.caocci@unica.it
Dott.ssa Marianna Greco
CTMO-EMATOLOGIA – Hospital: P.O Businco Via Jenner Cagliari
mgreco@unica.it
Prof. Mario Scartozzi
UOC di Oncologia Medica, Dipartimento di Scienze Mediche Mario Aresu, Asse E Cittadella Universitaria di Monserrato, Cagliari. marioscartozzi@unica.it - Tel. 070/51093217
Prof.ssa Clelia Madeddu
UOC di Oncologia Medica, Dipartimento di Scienze Mediche Mario Aresu, Asse E Cittadella Universitaria di Monserrato, Cagliari. Tel 070 6754228. E mail: clelia_md@yahoo.it
Dr.ssa Elena Massa
Dipartimento di Scienza Mediche Internistiche “Mario Aresu”, Policlinico Universitario, SS 554, Km 4.600, Spina Didattica, Studio n.43. Telefono 070 6754250. Email: emassa@medicina.unica.it

Office hours
By appointment. The location will be established in advance by the student and the lecturer via telephone or email.

Questionnaire and social

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