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Title Issue Date Author(s) Journal Publisher
Cholinium-Based Ionic Liquids from Hydroxycinnamic Acids as New Promising Bioactive Agents: A Combined Experimental and Theoretical Investigation 2021 Demurtas, Monica; Onnis, Valentina; Zucca, Paolo; Rescigno, Antonio; Lachowicz, Joanna Izabela; D...e Villiers Engelbrecht, Leon; Nieddu, Mariella; Ennas, Guido; Scano, Alessandra; Mocci, Francesca; Cesare Marincola, Flaminia ACS SUSTAINABLE CHEMISTRY & ENGINEERING
Response to Perspectives on the Classical Enzyme Carbonic Anhydrase and the Search for Inhibitors 2021 Angeli, Andrea; Carta, Fabrizio; Nocentini, Alessio; Winum, Jean-Yves; Zalubovskis, Raivis; Onnis..., Valentina; Eldehna, Wagdy M; Capasso, Clemente; Carradori, Simone; Donald, William A; Dedhar, Shoukat; Supuran, Claudiu T BIOPHYSICAL JOURNAL
Design, synthesis and in vitro and in vivo biological evaluation of flurbiprofen amides as new fatty acid amide hydrolase/cyclooxygenase-2 dual inhibitory potential analgesic agents 2021 Deplano, Alessandro; Karlsson, Jessica; Moraca, Federica; Svensson, Mona; Cristiano, Claudia; Mor...gillo, Carmine Marco; Fowler, Christopher J.; Russo, Roberto; Catalanotti, Bruno; Onnis, Valentina JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY
Synthesis, characterization, HSA/DNA interactions and antitumor activity of new [Ru(η6-p-cymene)Cl2(L)] complexes 2020 Đukić, Maja B.; Jeremić, Marija S.; Filipović, Ignjat P.; Klisurić, Olivera R.; Kojić, Vesna V.; ...Jakimov, Dimitar S.; Jelić, Ratomir M.; Onnis, Valentina; Matović, Zoran D. JOURNAL OF INORGANIC BIOCHEMISTRY
Synthesis and Biological Evaluation of 2-Substituted Benzyl-/Phenylethylamino-4-amino-5-aroylthiazoles as Apoptosis-Inducing Anticancer Agents 2020 Oliva, Paola; Onnis, Valentina; Balboni, Elisa; Hamel, Ernest; Estévez-Sarmiento, Francisco; Quin...tana, José; Estévez, Francisco; Brancale, Andrea; Ferla, Salvatore; Manfredini, Stefano; Romagnoli, Romeo MOLECULES
Ruthenium(II) Complexes of Isothiazole Ligands: Crystal Structure, HSA/DNA Interactions, Cytotoxic Activity and Molecular Docking Simulations 2020 Djukić, Maja B.; Jeremić, Marija S.; Filipović, Ignjat P.; Klisurić, Olivera R.; Jelić, Ratomir M....; Popović, Suzana; Matić, Sanja; Onnis, Valentina; Matović, Zoran D. CHEMISTRYSELECT
Exploring the fatty acid amide hydrolase and cyclooxygenase inhibitory properties of novel amide derivatives of ibuprofen 2020 Deplano, Alessandro; Karlsson, Jessica; Svensson, Mona; Moraca, Federica; Catalanotti, Bruno; Fow...ler, Christopher J.; Onnis, Valentina JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY
Sulfonamide/sulfamate switch with a series of piperazinylureido derivatives: Synthesis, kinetic and in silico evaluation as carbonic anhydrase isoforms I, II, IV, and IX inhibitors 2020 Nocentini, Alessio; Moi, Davide; Deplano, Alessandro; Osman, Sameh M.; AlOthman, Zeid A.; Balboni..., Gianfranco; Supuran, Claudiu T.; Onnis, Valentina EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
Synthesis and evaluation of antioxidant and antiproliferative activity of 2-arylbenzimidazoles 2020 Baldisserotto, Anna; Demurtas, Monica; Lampronti, Ilaria; Tacchini, Massimo; Moi, Davide; Balboni..., Gianfranco; Pacifico, Salvatore; Vertuani, Silvia; Manfredini, Stefano; Onnis, Valentina BIOORGANIC CHEMISTRY
Appliance of the piperidinyl-hydrazidoureido linker to benzenesulfonamide compounds: Synthesis, in vitro and in silico evaluation of potent carbonic anhydrase II, IX and XII inhibitors 2020 Moi, Davide; Nocentini, Alessio; Deplano, Alessandro; Osman, Sameh M.; AlOthman, Zeid A.; Piras, ...Valentina; Balboni, Gianfranco; Supuran, Claudiu T.; Onnis, Valentina BIOORGANIC CHEMISTRY
In-Vitro Evaluation of Antioxidant, Antiproliferative and Photo-Protective Activities of Benzimidazolehydrazone Derivatives 2020 Baldisserotto, Anna; Demurtas, Monica; Lampronti, Ilaria; Tacchini, Massimo; Moi, Davide; Balboni..., Gianfranco; Vertuani, Silvia; Manfredini, Stefano; Onnis, Valentina PHARMACEUTICALS
Carbonic anhydrase inhibitors targeting metabolism and tumor microenvironment 2020 Angeli, Andrea; Carta, Fabrizio; Nocentini, Alessio; Winum, Jean-Yves; Zalubovskis, Raivis; Akdem...ir, Atilla; Onnis, Valentina; Eldehna, Wagdy M.; Capasso, Clemente; Simone, Giuseppina De; Monti, Simona Maria; Carradori, Simone; Donald, William A.; Dedhar, Shoukat; Supuran, Claudiu T. METABOLITES
2-(Arylamino)-6-(trifluoromethyl)nicotinic Acid Derivatives: New HIV-1 RT Dual Inhibitors Active on Viral Replication 2020 Corona, Angela; Onnis, Valentina; Del Vecchio, Claudia; Esposito, Francesca; Cheng, Yung-Chi; Tra...montano, Enzo MOLECULES
The fatty acid amide hydrolase and cyclooxygenase-inhibitory properties of novel amide derivatives of carprofen 2020 Deplano, Alessandro; Karlsson, Jessica; Fowler, Christopher J.; Onnis, Valentina BIOORGANIC CHEMISTRY
Synthesis and in vitro evaluation of piperazinyl-ureido sulfamates as steroid sulfatase inhibitors 2019 Moi, Davide; Foster, Paul A.; Rimmer, Lucy G.; Jaffri, Alisha; Deplano, Alessandro; Balboni, Gian...franco; Onnis, Valentina; Potter, Barry V. L. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
Structure-activity relationship with pyrazoline-based aromatic sulfamates as carbonic anhydrase isoforms I, II, IX and XII inhibitors: Synthesis and biological evaluation 2019 Moi, Davide; Nocentini, Alessio; Deplano, Alessandro; Balboni, Gianfranco; Supuran, Claudiu T.; O...nnis, Valentina EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
Indole derivatives as multifunctional drugs: Synthesis and evaluation of antioxidant, photoprotective and antiproliferative activity of indole hydrazones 2019 Demurtas, Monica; Baldisserotto, Anna; Lampronti, Ilaria; Moi, Davide; Balboni, Gianfranco; Pacif...ico, Salvatore; Vertuani, Silvia; Manfredini, Stefano; Onnis, Valentina BIOORGANIC CHEMISTRY
Benzylamides and piperazinoarylamides of ibuprofen as fatty acid amide hydrolase inhibitors 2019 Deplano, Alessandro; Cipriano, Mariateresa; Moraca, Federica; Novellino, Ettore; Catalanotti, Bru...no; Fowler, Christopher J.; Onnis, Valentina JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY
Targeting prokineticin system counteracts hypersensitivity, neuroinflammation, and tissue damage in a mouse model of bortezomib-induced peripheral neuropathy 2019 Moschetti, Giorgia; Amodeo, Giada; Maftei, Daniela; Lattanzi, Roberta; Procacci, Patrizia; Sartor...i, Patrizia; Balboni, Gianfranco; Onnis, Valentina; Conte, Vincenzo; Panerai, Alberto; Sacerdote, Paola; Franchi, Silvia JOURNAL OF NEUROINFLAMMATION
Synthesis and biological evaluation of novel pyrazoline-based aromatic sulfamates with potent carbonic anhydrase isoforms II, IV and IX inhibitory efficacy 2018 Nocentini, Alessio; Moi, Davide; Balboni, Gianfranco; Salvadori, Severo; Onnis, Valentina; Supura...n, Claudiu T. BIOORGANIC CHEMISTRY
Benzofuran hydrazones as potential scaffold in the development of multifunctional drugs: Synthesis and evaluation of antioxidant, photoprotective and antiproliferative activity 2018 Baldisserotto, Anna; Demurtas, Monica; Lampronti, Ilaria; Moi, Davide; Balboni, Gianfranco; Vertu...ani, Silvia; Manfredini, Stefano; Onnis, Valentina EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
Discovery of thiazolin-4-one-based aromatic sulfamates as a new class of carbonic anhydrase isoforms I, II, IV, and IX inhibitors 2018 Nocentini, Alessio; Moi, Davide; Balboni, Gianfranco; Onnis, Valentina; Supuran, Claudiu T. BIOORGANIC CHEMISTRY
Novel propanamides as fatty acid amide hydrolase inhibitors 2017 Deplano, Alessandro; Morgillo, Carmine Marco; Demurtas, Monica; Björklund, Emmelie; Cipriano, Mar...iateresa; Svensson, Mona; Hashemian, Sanaz; Smaldone, Giovanni; Pedone, Emilia; Luque, F. Javier; Cabiddu, MARIA GRAZIA; Novellino, Ettore; Fowler, Christopher J.; Catalanotti, Bruno; Onnis, Valentina EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
Antagonism of EG-VEGF receptors as targeted therapy for choriocarcinoma progression in vitro and in vivo 2017 Traboulsi, Wael; Sergent, Frederic; Boufettal, Houssine; Brouillet, Sophie; Slim, Rima; Hoffmann,... Pascale; Benlahfid, Mohammed; Zhou, qun yong; Balboni, Gianfranco; Onnis, Valentina; Bolze, Pierre Adrien; Salomon, Aude; Sauthier, Philippe; Mallet, François; Aboussaouira, Touria; Feige, Jean Jacques; Benharouga, Mohamed; Alfaidy, Nadia CLINICAL CANCER RESEARCH
Haloacetophenones as newly potent nematicides against Meloidogyne incognita 2017 Tocco, Graziella; Eloh, Kodjo; Onnis, Valentina; Sasanelli, Nicola; Caboni, Pierluigi INDUSTRIAL CROPS AND PRODUCTS
3,4-Dihydroquinazoline derivatives inhibit the activities of cholinesterase enzymes 2017 Park, Byeongyeon; Nam, Ji Hye; Kim, Jin Han; Kim, Hyoung Ja; Onnis, Valentina; Balboni, Gianfranc...o; Lee, Kyung Tae; Park, Jeong Ho; Catto, Marco; Carotti, Angelo; Lee, Jae Yeol BIOORGANIC & MEDICINAL CHEMISTRY LETTERS Elsevier Ltd
Design, synthesis and antiviral evaluation of novel heteroarylcarbothioamide derivatives as dual inhibitors of HIV-1 Reverse transcriptase-associated RNase H and RDDP functions 2017 Corona, Angela; Onnis, Valentina; Deplano, Alessandro; Bianco, Giulia; Demurtas, Monica; Distinto..., Simona; Cheng, Yung Chi; Alcaro, Stefano; Esposito, Francesca; Tramontano, Enzo PATHOGENS AND DISEASE
Discovery of a novel class of profen derivatives as FAAH inhibitors: MD and QM/MM studies of the binding mode and 3D SAR 2016 Morgillo, CM; Deplano, A; Karlsson, J; Cipriano, M; Björklund, E; Fowler, Cj; Onnis, V; Luque, Fj...; Catalanotti, B
DESIGN, SYNTHESIS AND PHARMACOLOGICAL INVESTIGATION OF NEW DNA METHYLTRANSFERASE INHIBITORS 2016 Balboni, Gianfranco; Deplano, Alessandro; Demurtas, Monica; Arimondo, Paola B.; Masson, Veronique...; Onnis, Valentina
Effect of the T-type channel blocker KYS-05090S in mouse models of acute and neuropathic pain 2016 M'Dahoma, Saïd; Gadotti, Vinicius M; Zhang, Fang Xiong; Park, Byeongyeon; Nam, Ji Hye; Onnis, Val...entina; Balboni, Gianfranco; Lee, Jae Yeol; Zamponi, Gerald W. PFLÜGERS ARCHIV
Design, synthesis and evaluation of antiproliferative activity of new benzimidazolehydrazones 2016 Onnis, V; Demurtas, M; Deplano, A; Balboni, G; Baldisserotto, A; Manfredini, S; Pacifico, S; Liek...ens, S; Balzarini, J MOLECULES
Antagonism of the prokineticin system prevents and reverses allodynia and inflammation in a mouse model of diabetes 2016 Castelli, M; Amodeo, G; Negri, L; Lattanzi, R; Maftei, D; Gotti, C; Pistillo, F; Onnis, V; Congiu..., C; Panerai, AE; Sacerdote, P; Franchi, S PLOS ONE
Potent nematicidal activity of maleimide derivatives on Meloidogyne incognita 2016 Eloh, K; Demurtas, M; Mura, MG; Deplano, A; Onnis, V; Sasanelli, N; Maxia, A; Caboni, P JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
Nematicidal activity of acetophenones and chalcones against Meloidogyne incognita and structure-activity considerations 2016 Caboni P; Aissani N; Demurtas M; Ntalli N; Onnis V PEST MANAGEMENT SCIENCE
Investigation of the mechanism of FAAH inhibition of profen amide derivatives 2015 Morgillo, CM; Deplano, A; Demurtas, M; Karlosson, J; Onnis, V; Congiu, C; Fowler, CJ; Catalanotti, B
Interaction of the N-(3-Methylpyridin-2-yl)amide derivatives of flurbiprofen and ibuprofen with FAAH: Enantiomeric selectivity and binding mode 2015 Karlsson, Jessica; Morgillo, Carmine M; Deplano, Alessandro; Smaldone, Giovanni; Pedone, Emilia; ...Luque, F. Javier; Svensson, Mona; Novellino, Ettore; Congiu, Cenzo; Onnis, Valentina; Catalanotti, Bruno; Fowler, Christopher J. PLOS ONE
PPAR controls pregnancy outcome through activation of EG-VEGF: new insights into the mechanism of placental development 2015 Vanessa Garnier; Wael Traboulsi; Aude Salomon; Sophie Brouillet; Thierry Fournier; Carine Winkler...; Beatrice Desvergne; Pascale Hoffmann; Qun-Yong Zhou; Cenzo Congiu; Valentina Onnis; Mohamed Benharouga; Jean-Jacques Feige; Nadia Alfaidy AMERICAN JOURNAL OF PHYSIOLOGY: ENDOCRINOLOGY AND METABOLISM
In vitro nematicidal activity of aryl hydrazones and comparative GC-MS metabolomics analysis 2015 Eloh, K; Demurtas, M; Deplano, A; Ngoutane Mfopa, A; Murgia, A; Maxia, A; Onnis, V; Caboni, P JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
Synthesis and carbonic anhydrase I, II, IX and XII inhibitory activity of sulfamates incorporating piperazinyl-ureido moieties 2015 Congiu, Cenzo; Onnis, Valentina; Deplano, Alessandro; Balboni, Gianfranco; Ceruso, Mariangela; Su...puran, Claudiu T. BIOORGANIC & MEDICINAL CHEMISTRY
TRPV1 modulators: synthesis and in vitro evaluation of 1-heteroarylpiperidinecarboxamide and piperazinylurea derivatives 2015 Congiu, C; Onnis, V; Balboni, G; Schiano-Moriello, A; Di Marzo, V; De Petrocellis, L EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
Synthesis of sulfonamides incorporating piperazinyl-ureido moieties and their carbonic anhydrase I, II, IX and XII inhibitory activity 2015 Congiu, Cenzo; Onnis, Valentina; Deplano, Alessandro; Balboni, Gianfranco; Dedeoglu, Nurcan; Supu...ran, Claudiu T. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
Design, synthesis, and anti-HIV-1 activity of 1-substituted 3-(3,5-dimethylbenzyl)triazine derivatives 2015 Sakakibara, Norikazu; Balboni, Gianfranco; Congiu, Cenzo; Onnis, Valentina; Demizu, Yosuke; Misaw...a, Takashi; Kurihara, Masaaki; Kato, Yoshihisa; Maruyama, Tokumi; Toyama, Masaaki; Okamoto, Mika; Baba, Masanori ANTIVIRAL CHEMISTRY & CHEMOTHERAPY
Critical role for prokineticin 2 in CNS autoimmunity 2015 ABOU HAMDAN, M; Costanza, M; Fontana, E; DI DARIO, M; Musio, S; Congiu, Cenzo; Onnis, Valentina; ...Lattanzi, R; Radaelli, M; Martinelli, V; Salvadori, S; Negri, L; Poliani, Pl; Farina, C; Balboni, Gianfranco; Steinman, L; Pedotti, R. NEUROLOGY® NEUROIMMUNOLOGY & NEUROINFLAMMATION
Characterisation of (R)-2-(2-Fluorobiphenyl-4-yl)-N-(3-Methylpyridin-2-yl)Propanamide as a Dual Fatty Acid Amide Hydrolase: Cyclooxygenase Inhibitor 2015 Gouveia-Figueira, S; Karlsson, J; Deplano, A; Hashemian, S; Svensson, M; Fredriksson Sundbom, M; ...Congiu, C; Onnis, V; Fowler, Cj PLOS ONE
Inhibitory effect of positively charged triazine antagonists of prokinecitin receptors on the transient receptor vanilloid type-1 (TRPV1) channel 2015 Petrocellis, Luciano De; Moriello, Aniello Schiano; Byun, Joon Seok; Sohn, Joo Mi; Lee, Jae Yeol;... Vázquez-Romero, Ana; Garrido, Maria; Messeguer, Angel; Zhang, Fang-Xiong; Zamponi, Gerald W; Deplano, Alessandro; Congiu, Cenzo; Onnis, Valentina; Balboni, Gianfranco; Marzo, Vincenzo Di PHARMACOLOGICAL RESEARCH
Halogenated triazinediones behave as antagonists of PKR1: in vitro and in vivo pharmacological characterization 2014 Lattanzi, R; Congiu, Cenzo; Onnis, Valentina; Deplano, Alessandro; Salvadori, S; Marconi, V; Maft...ei, D; Francioso, A; Ambrosio, C; Casella, I; Costa, T; Caltabiano, G; Matsoukas M., T; Balboni, Gianfranco; Negri, L. INTERNATIONAL JOURNAL OF PHARMACEUTICAL SCIENCES AND RESEARCH
Design, synthesis and pharmacological investigation on new FAAH inhibitors 2014 Onnis V; Congiu C; Deplano A; Demurtas M; Cipriano M; Fowler C.J; Morgillo C.M; Catalanotti B CHEMMEDCHEM
An important role for prokineticin 2 in autoimmune CNS demyelination 2014 Abou-hamdan M.; Costanza M.; Fontana E.; Musio S.; Di Dario M.; Congiu C.; Onnis V; Lattanzi R.; ...Negri L.; Poliani P.L.; Farina C.; Balboni G.; Steinman L.; Pedotti R. JOURNAL OF NEUROIMMUNOLOGY
Design, Synthesis and Evaluation of new 2-(Arylidenehydrazino)pyrrole Derivatives as Potential Antitumor Agents 2014 Congiu C; Onnis V; Deplano A; Demurtas M; Balboni G CHEMMEDCHEM
Synthesis and carbonic anhydrase I, II, IX and XII inhibition studies of 4-N,N-disubstituted sulfanilamides incorporating 4,4,4-trifluoro-3-oxo-but-1-enyl, phenacylthiourea and imidazol-2(3H)-one/thione moieties 2014 Congiu C; ONNIS V; Balboni G; Supuran CT BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

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