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Professor
LAURA DAZZI (Tit.)
Period
Second Semester 
Teaching style
Convenzionale 
Lingua Insegnamento
INGLESE 



Informazioni aggiuntive

Course Curriculum CFU Length(h)
[60/72]  NEUROPSYCHOBIOLOGY [60/72-00 - Ord. 2020]  PERCORSO COMUNE 3 36

Objectives

Acquisition of knowledge on key behavioral models in laboratory animals and on methods of detection and processing of data for the planning and execution of a behavioral study.
After completing the course the student will be able to appreciate the usefulness of behavioral tests for the study of key aspects of human disease, to understand the basic functional mechanisms and for the testing of various therapeutic options.
The student will also be able to develop critical thinking and independent judgment to evaluate the advantages and limitations of different experimental models and to critically analyze the literature on animal models with respect to the description and interpretation of the data. A key objective will be to make sure that the student is aware of the great care of the welfare of experimental animals that animal research requires and of the legislation that regulates the use of animals for experimentation.

Prerequisites

Solid knowledge of the main neurotransmitter systems and of the superior functions that they regulate

Contents

Introduction to animal models. The concept of animal model. Animal model validation: Face validity, predictive validity, contruct validity. The choice of model and the research protocol.
Species of animals used in biomedical research. http: //www.nih.gov/science/models/ overview of the major animal models: Invertebrates (C. elegans, D. melanogaster; Aplysia). Vertebrates (zebrafish, chick, rodents, primates) - translational features of the model and the data.
Experimental procedures. The European Directive 2010/63 on the use of animals in research. Legislation and 3 R. The health of laboratory animals.
Analysis of some animal models of pathology: depression; anxiety; schizophrenia; epilepsy; Alzheimer; Parkinson; Multiple Sclerosis; addiction; Cognition and memory.
The animal facility: farming techniques, maintenance and handling of rodents. Animal welfare.
Insights into specific topics by presentation by students of selected scientific papers that will be discussed collectively and critically under the supervision of the teacher.

Teaching Methods

3 CFU (36 hours) of laboratory
The teaching will be delivered simultaneously both in presence and online, thus outlining a mixed teaching that can be enjoyed in university classrooms but at the same time also at a distance. At the beginning of the semester, the student will opt for face-to-face or distance teaching, the choice will be binding for the entire semester. If the number of students exceeds the capacity of the classrooms, determined on the basis of government provisions on health matters for the purpose of combating the pandemic by Covid-19, access to teaching facilities will be regulated through a shift system that will be communicated in due time to interested students.

Verification of learning

The modality of the final exam will be defined depending on the provisions aimed at containing the pandemic.
Judgement
The final grade takes into account several factors:
Quality of the knowledge, skills, competences:
a) appropriateness, accuracy and consistency of knowledge
b) appropriateness, accuracy and consistency of skills
c) appropriateness, accuracy and consistency of skills
Exhibition mode:
a) Capacity of expression;
b) Proper use of the specific language of the discipline;
c) Logical capacity;
e) Ability to connect different arguments by finding the common points and establish a consistent overall design, ie taking care of structure, organization and logical connections of speech exhibition;
f) Ability to summarize also through the use of symbolism on the matter, and graphic expression of ideas and concepts, for example in the form of formulas, tables, equations.
Relational qualities:
Availability to exchange and interaction with the teacher during the interview.
Personal qualities:
a) critical spirit;
b) ability to self-evaluation.

Consequently, the judgment can be:
a) Fair (18 to 20/30)
The candidate demonstrates little knowledge acquired, superficial level, many gaps. Expressive abilities are modest, but still sufficient to support a coherent dialogue, logical and consequential in the fitting of the subjects of the elementary level; poor capacity for synthesis and ability to graphic expression rather stunted, lack of interaction with the teacher during interview.
b) Moderate (21 to 23)
The applicant demonstrates discreet acquisition of knowledge but lack of depth, a few gaps; expressive abilities more than sufficient to support a coherent dialogue; acceptable mastery of the language of science, logical and consequential in the fitting of the arguments of moderate complexity, more than sufficient capacity for synthesis and acceptable ability to graphic expression.
c) Good (24 to 26)
The candidate demonstrates a large wealth of knowledge, moderate depth, with small gaps; satisfactory mastery of the expressive capabilities and significant scientific language; dialogical and critical ability well detectable, good capacity for synthesis and ability to graphic expression more than acceptable.
d) Outstanding (27 to 29)
The candidate demonstrates an extensive wealth of notions, good depth, with marginal gaps; remarkable powers of expression and high mastery of scientific language; remarkable dialogue capacity, good competence and relevant aptitude for logic synthesis, high capacity for synthesis and graphic expression.
e) Excellent (30)
The candidate demonstrates a very extensive wealth of and in-depth knowledge, irrelevant gaps, high capacity and high mastery of the expressive language of science; excellent dialogical ability, aptitude to make connections between different subjects, excellent ability to synthesize and is very familiar with the expression graphics.
The laude is attributed to the candidates clearly above average, and whose notional limits, if any, expressive, conceptual, logical, as a whole are completely irrelevant.

Texts

Reviews, publications and notes on the topics of the course provided by the teacher

More Information

During the classes the teacher will provide the students with lecture notes, reviews and publications on the topics of the course

Questionnaire and social

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