Department of Life and Environmental Sciences

 

Education
1989: master degree in Pharmaceutical Chemistry and Technology at University of Cagliari.
1990: master degree in Pharmacy at University of Cagliari.

Employment:
1991-2001: Graduated technician at the University of Cagliari.
2001 -2014: Medicinal Chemistry Assistant Professor (Department of Life and Environmental Sciences, Unit of Drug Sciences, University of Cagliari).
2015- :Medicinal Chemistry Associate Professor (Department of Life and Environmental Sciences, Unit of Drug Sciences, University of Cagliari).

2004-2010: Member, Board of the PhD program in Pharmaceutical Sciences (University of Ferrara).
2006-2011: Member, Board of the PhD program in Toxicology (University of Cagliari).
2011-2016: Member, Board of the PhD program in Pharmaceutical Science and technologies (University of Cagliari)
2013-: Member, Board of the Phd program in Life, Envinronmental and Drug Sciences (University of Cagliari)

Teaching
From 2001: Professor, Drug Analisys (School of Pharmacy, University of Cagliari)
From 2011: Professor, Medicinal Chemistry (School of Pharmacy, University of Cagliari)

Professional Societies:
Member of Italian Chemical Society

Scientific activity: The major research interests are: 1) the design and synthesis of biologically active compounds, especially antitumor, analgesic antimicrobial agents, enzyme inhibitors 2) development of new methodology for the synthesis of nitrogen heterocycles.
In the last years the research was focused on
- non peptide antagonists prokineticin receptors
- heterocyclic molecules endowed with antiproliferative activity on cancer cells
- hydrazones endowed with antioxidant and antiproliferative activity
- derivatives of NSADIDs and polynitrogenhetrocycles as FAAH and COX inhibitors
- heterocyclic amides as TRPV! modulators
- quinazoline and aminoflavone derivatives endowed with antioxidant and Acetylcholine esterase inhibitory activity
- heteroarylhydrazones endowed with antioxidant, photoprotective and antiproliferative activity
- triazine, carbothioamides and pyridine derivative endowed with antiviral activity
- aromatic and heteroaromatic sulfonaminides and sulfamtes as carbonic anhydrase inhibitors
- chalcones, hydrazone and maleimide derivitives endowed with nematicidal activity d

Reviewer for Journal of Medicinal Chemistry, Bioorganic & Medicinal Chemistry, Bioorganic & Medicinal Chemistry Letters, European Journal of Medicinal Chemistry,Journal of Organic Chemistry, Tetrahedron Letters, Molecules, Bioorganic Chemistry.
Author or co-author of about 110 papers on international journals.



 

 

 



 

Questionnaire and social

Share on: